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for Monoclonal Antibodies
254 pages, incl. index
today's world, where time always seems too short, a book like this is of
enormous value, condensing masses of real-life practical knowledge into
an accessible single source. This book certainly makes worthy
read the entire review...
Purification Tools for Monoclonal Antibodies is an essential book for professionals, educators & advanced students in the field of Biotechnology. It is based on experience gained from purification process development, scale-up, & manufacture of more than 250 monoclonal-based diagnostic & therapeutic products. Ten chapters provide in-depth coverage of major separation mechanisms, process strengths, weaknesses & method development; all fully integrated with the special performance, economic & validation requirements associated with monoclonals. Covered methods include precipitation with inorganic salts, polyethylene glycol, electrolyte depletion, caprylic acid, ethacridine, chromatographic purification by size exclusion, ion exchange, hydroxyapatite, hydrophobic interaction, immobilized metal affinity, hydrophilic interaction, euglobulin adsorption, thiophilic adsorption, protein A, protein G, lectin affinity, & more...
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